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Introduction
Atopic eczema (AE) is an inflammatory skin disorder which is characterized by dry and itchy skin and a cutaneous hyperreactivity to environmental triggers. It affects at least 15% of children and 2-10% of adults and often predates the development of allergic airway diseases. Given its substantial prevalence, which has seen an enormous rise especially in industrialized nations, and the lack of cure, there is a pressing need to better understand its pathophysiology. It is generally recognized that AE is triggered through unknown environmental factors precipitating a polygenic risk background into disease manifestation. Recent evidence from molecular genetics underscores the importance of the skin barrier genes in addition to genes promoting abnormal immunological pathways.
To reveal the mechanisms by which environmental factors pursue the genetic predisposition into disease manifestation, a multi-disciplinary approach is needed with complementary experimental approaches including both in vivo studies and validated animal and in vitro models. This COST Action (BM0903) will bring together experts from 22 institutions in 11 COST countries engaged in epidemiology, genetics, clinical research and research on skin barrier and immunology. SKINBAD will cross-link 5 Work Groups allowing interdisciplinary and translational research facilitating the development of more targeted prevention and treatment strategies.
Calendar
23-24 May 2012
COST Workshop: "Structure and function of the Skin Barrier’’ + WG meetings
Location: Lyon, France
Local organiser: Marek Haftek (marek.haftek@univ-lyon1.fr)
Program SCUR 2012 (pdf, 76 kb)
31st May: STSM Call Dead Lines
10-12 September 2012
Training School in Immunology & Genetics of Atopic Dermatitis
Location: Split, Croatia
Local organizer: Ivone Jakasa (ywone04@gmail.com)
Click here for: Training School
18-19 September 2012
COST Workshop: "Epidermal barrier in Atopic Dermatitis’’ + WG meetings
(a joint workshop with E2BRN during ESDR meeting)
Location: Venice, Italy
30st September: STSM Call Dead Lines
last update: 20, April 2012